Same how does it work

So, while Scott thinks that SAMe can be effective in treating depression, she says that the dosage is going to vary from person-to-person.

But some people are allergic, and folks with mental health issues should be aware that SAMe can trigger mania. Also, SAMe does not mix well with antidepressants or many other psychopharmaceuticals and supplements, so be careful. Most of the studies on SAMe are pretty small, so there is some, but not a ton of, clinical evidence to bolster the claims of SAMe supplements. By Tracey Anne Duncan. What is SAMe, exactly? The site includes questions and answers about clinical trials, guidance on how to find clinical trials through ClinicalTrials.

Clinical trials are necessary to find better ways to prevent, diagnose, and treat diseases. To provide resources that help answer health questions, MedlinePlus a service of the National Library of Medicine brings together authoritative information from the National Institutes of Health as well as other Government agencies and health-related organizations.

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Depression and Complementary Health Approaches. How much do we know about SAMe? What do we know about the effectiveness of SAMe? What do we know about the safety of SAMe? Data on the long-term safety of SAMe and its safety for use during pregnancy are too limited to draw any conclusions.

SAMe may not be safe for people with bipolar disorder. SAMe may interact with some medicines or other dietary supplements.

What Is SAMe? Overall, the evidence that oral SAMe may be helpful for depression is not conclusive. At BrainMD, we see your brain as a sophisticated supercomputer with both hardware and software. For peak efficiency, the machinery including cells, connections, chemicals, energy, blood flow, and waste processing needs to work effectively. Whenever feasible, we recommend the most natural ways to heal and support the brain, such as supplements and lifestyle interventions — nutrition plans and workout prescriptions, for example.

In some countries in Europe, SAMe is a prescription drug. SAMe can be taken orally, through a muscular injection or by IV. People generally use SAMe to treat depression, osteoarthritis and liver disease. However, SAMe can also interact with antidepressant medications.

SAMe appears to be safe and might be effective in treating depression and osteoarthritis. However, SAMe might interact with antidepressants. Don't use SAMe and prescription antidepressants together. If you have bipolar disorder, don't take SAMe without talking to your doctor first.

The supplement might increase anxiety and mania. If you have a compromised immune system, talk to your doctor before taking SAMe. People who have a weakened immune system may be at increased risk of an infection caused by bacteria known as pneumocystis. SAMe may boost this microorganism's growth.